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STD/STI Education Guide: Many STIs have NO symptoms.

The Ultimate STD/STI Education Guide


CDC Sexually Transmitted Infections Resource Center

Real facts. No shame. Smart health choices for teens and adults.

Important: STDs/STIs are extremely common and many people have no symptoms at all. Testing, treatment, vaccines, and safer sex practices help protect your health and future fertility.

STD/STI Basics Everyone Should Know

  • Many STIs have NO symptoms.
  • Condoms reduce risk but do not prevent every STI.
  • Vaccines exist for HPV and Hepatitis B.
  • Early treatment helps prevent complications.
  • Testing is part of normal healthcare.
  • Untreated STIs can affect fertility, pregnancy, and long-term health.

CDC – STI Prevention

1. Chlamydia

Chlamydia is one of the most common bacterial STIs, especially in teens and young adults.

  • Symptoms: burning urination, discharge, pelvic pain, or no symptoms.
  • Spread: vaginal, anal, or oral sex.
  • Treatment: antibiotics.
  • Risk: untreated infections can affect fertility.

CDC – Chlamydia
MedlinePlus – Chlamydia

2. Gonorrhea

Gonorrhea is a bacterial STI that can infect the genitals, throat, and rectum.

  • Symptoms: discharge, burning urination, pelvic pain, sore throat.
  • Treatment: antibiotics.
  • Important: antibiotic-resistant gonorrhea is increasing.

CDC – Gonorrhea
Mayo Clinic – Gonorrhea

3. Syphilis

Syphilis is a bacterial infection that develops in stages and can become very serious if untreated.

  • Early sign: painless sore (chancre).
  • Later symptoms: rash, fever, nerve damage.
  • Treatment: penicillin antibiotics.

CDC – Syphilis
NHS – Syphilis

4. HIV

HIV attacks the immune system. Treatment allows many people with HIV to live long healthy lives.

  • Symptoms: flu-like illness early on, or no symptoms.
  • Treatment: antiretroviral therapy (ART).
  • Prevention: condoms, testing, PrEP.

CDC – HIV
NIH HIV Info

5. Human Papillomavirus (HPV)

HPV is the most common STI in the world.

  • Symptoms: often none.
  • Can cause: genital warts and some cancers.
  • Protection: HPV vaccine.

CDC – HPV
FDA – HPV Vaccine

6. Genital Herpes (HSV-1 & HSV-2)

Herpes is a viral STI that causes outbreaks of sores or blisters.

  • Symptoms: painful blisters or sores.
  • Spread: skin-to-skin contact.
  • Treatment: antiviral medicine helps reduce outbreaks.

CDC – Herpes
WebMD – Genital Herpes

7. Hepatitis B

Hepatitis B is a viral infection affecting the liver.

  • Symptoms: fatigue, jaundice, nausea.
  • Spread: blood, semen, body fluids.
  • Prevention: vaccine.

CDC – Hepatitis B
MedlinePlus – Hepatitis B

8. Hepatitis C

Hepatitis C mainly spreads through blood contact and can damage the liver.

  • Symptoms: often none for years.
  • Treatment: antiviral medications can cure many cases.

CDC – Hepatitis C
Mayo Clinic – Hepatitis C

9. Trichomoniasis

Trichomoniasis is caused by a parasite.

  • Symptoms: itching, discharge, odor, burning.
  • Treatment: prescription antibiotics.

CDC – Trichomoniasis
MedlinePlus – Trichomoniasis

10. Pubic Lice (“Crabs”)

Pubic lice are tiny insects that attach to pubic hair.

  • Symptoms: itching and visible lice or eggs.
  • Treatment: medicated lotions or shampoos.

CDC – Pubic Lice

11. Scabies

Scabies is caused by tiny mites that burrow into the skin.

  • Symptoms: intense itching and rash.
  • Spread: close skin contact.
  • Treatment: prescription creams.

CDC – Scabies

12. Molluscum Contagiosum

Molluscum contagiosum is a viral skin infection.

  • Symptoms: small raised bumps.
  • Spread: skin contact.
  • Treatment: sometimes resolves on its own.

CDC – Molluscum Contagiosum

13. Mycoplasma Genitalium

Mycoplasma genitalium is a bacterial STI linked to urethritis and pelvic infections.

  • Symptoms: burning, discharge, pelvic pain.
  • Treatment: specific antibiotics.

CDC – Mycoplasma Genitalium

14. Chancroid

Chancroid is a bacterial STI that causes painful sores.

  • Symptoms: genital ulcers and swollen lymph nodes.
  • Treatment: antibiotics.

CDC – Chancroid

15. Lymphogranuloma Venereum (LGV)

LGV is a rare type of chlamydia infection.

  • Symptoms: sores, swollen lymph nodes, rectal symptoms.
  • Treatment: antibiotics.

CDC – LGV

16. Granuloma Inguinale (Donovanosis)

This rare bacterial STI causes progressive genital sores.

  • Symptoms: painless beefy-red sores.
  • Treatment: antibiotics.

CDC – Donovanosis

17. Ureaplasma

Ureaplasma bacteria may sometimes contribute to urinary or genital symptoms.

  • Symptoms: irritation, discharge, pelvic discomfort.
  • Treatment: antibiotics when needed.

MedlinePlus

18. Pelvic Inflammatory Disease (PID)

PID is a serious infection of female reproductive organs, often caused by untreated STIs.

  • Symptoms: pelvic pain, fever, discharge.
  • Risk: infertility if untreated.

CDC – PID
Mayo Clinic – PID

19. Bacterial Vaginosis (BV)

BV is caused by an imbalance of normal vaginal bacteria.

  • Symptoms: odor, discharge, irritation.
  • Treatment: antibiotics.

CDC – Bacterial Vaginosis

20. Yeast Infection

Yeast infections are fungal infections that are not always sexually transmitted but can occur after sex or antibiotic use.

  • Symptoms: itching, thick white discharge, irritation.
  • Treatment: antifungal medication.

MedlinePlus – Yeast Infections

STD/STI Quiz Challenge (30 Questions)

  1. What does STI stand for?
    Answer: Sexually Transmitted Infection.
  2. Can someone have an STI without symptoms?
    Answer: Yes.
  3. Which STI is the most common worldwide?
    Answer: HPV.
  4. What protects against many STIs?
    Answer: Condoms.
  5. Which STI can be prevented with a vaccine?
    Answer: HPV and Hepatitis B.
  6. What bacteria causes chlamydia?
    Answer: Chlamydia trachomatis.
  7. What STI can cause genital warts?
    Answer: HPV.
  8. Can HIV be treated?
    Answer: Yes.
  9. What organ does hepatitis affect?
    Answer: The liver.
  10. What STI commonly causes painful blisters?
    Answer: Herpes.
  11. Can untreated STIs affect fertility?
    Answer: Yes.
  12. What parasite causes trichomoniasis?
    Answer: Trichomonas vaginalis.
  13. What STI may cause a painless sore?
    Answer: Syphilis.
  14. Can oral sex spread STIs?
    Answer: Yes.
  15. What does PID stand for?
    Answer: Pelvic Inflammatory Disease.
  16. Can condoms reduce HIV risk?
    Answer: Yes.
  17. What STI is known as “crabs”?
    Answer: Pubic lice.
  18. Can gonorrhea infect the throat?
    Answer: Yes.
  19. What STI attacks the immune system?
    Answer: HIV.
  20. Can bacterial STIs usually be cured?
    Answer: Many can with antibiotics.
  21. What STI is caused by mites?
    Answer: Scabies.
  22. What STI often has no symptoms in women?
    Answer: Chlamydia.
  23. What medicine type treats fungal infections?
    Answer: Antifungal medication.
  24. Can teens get STIs?
    Answer: Yes.
  25. Should sexual partners be tested too?
    Answer: Yes.
  26. Can STI testing be part of routine healthcare?
    Answer: Yes.
  27. What is PrEP used for?
    Answer: HIV prevention.
  28. What STI can increase cancer risk?
    Answer: HPV.
  29. Can early treatment help prevent complications?
    Answer: Yes.
  30. Is getting tested something to feel ashamed about?
    Answer: No.

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