The Ultimate STD/STI Education Guide
CDC Sexually Transmitted Infections Resource Center
Real facts. No shame. Smart health choices for teens and adults.
Important: STDs/STIs are extremely common and many people have no symptoms at all. Testing, treatment, vaccines, and safer sex practices help protect your health and future fertility.
Quick Jump — 20 Common STDs/STIs
STD/STI Basics Everyone Should Know
- Many STIs have NO symptoms.
- Condoms reduce risk but do not prevent every STI.
- Vaccines exist for HPV and Hepatitis B.
- Early treatment helps prevent complications.
- Testing is part of normal healthcare.
- Untreated STIs can affect fertility, pregnancy, and long-term health.
1. Chlamydia
Chlamydia is one of the most common bacterial STIs, especially in teens and young adults.
- Symptoms: burning urination, discharge, pelvic pain, or no symptoms.
- Spread: vaginal, anal, or oral sex.
- Treatment: antibiotics.
- Risk: untreated infections can affect fertility.
2. Gonorrhea
Gonorrhea is a bacterial STI that can infect the genitals, throat, and rectum.
- Symptoms: discharge, burning urination, pelvic pain, sore throat.
- Treatment: antibiotics.
- Important: antibiotic-resistant gonorrhea is increasing.
3. Syphilis
Syphilis is a bacterial infection that develops in stages and can become very serious if untreated.
- Early sign: painless sore (chancre).
- Later symptoms: rash, fever, nerve damage.
- Treatment: penicillin antibiotics.
4. HIV
HIV attacks the immune system. Treatment allows many people with HIV to live long healthy lives.
- Symptoms: flu-like illness early on, or no symptoms.
- Treatment: antiretroviral therapy (ART).
- Prevention: condoms, testing, PrEP.
5. Human Papillomavirus (HPV)
HPV is the most common STI in the world.
- Symptoms: often none.
- Can cause: genital warts and some cancers.
- Protection: HPV vaccine.
6. Genital Herpes (HSV-1 & HSV-2)
Herpes is a viral STI that causes outbreaks of sores or blisters.
- Symptoms: painful blisters or sores.
- Spread: skin-to-skin contact.
- Treatment: antiviral medicine helps reduce outbreaks.
7. Hepatitis B
Hepatitis B is a viral infection affecting the liver.
- Symptoms: fatigue, jaundice, nausea.
- Spread: blood, semen, body fluids.
- Prevention: vaccine.
8. Hepatitis C
Hepatitis C mainly spreads through blood contact and can damage the liver.
- Symptoms: often none for years.
- Treatment: antiviral medications can cure many cases.
9. Trichomoniasis
Trichomoniasis is caused by a parasite.
- Symptoms: itching, discharge, odor, burning.
- Treatment: prescription antibiotics.
10. Pubic Lice (“Crabs”)
Pubic lice are tiny insects that attach to pubic hair.
- Symptoms: itching and visible lice or eggs.
- Treatment: medicated lotions or shampoos.
11. Scabies
Scabies is caused by tiny mites that burrow into the skin.
- Symptoms: intense itching and rash.
- Spread: close skin contact.
- Treatment: prescription creams.
12. Molluscum Contagiosum
Molluscum contagiosum is a viral skin infection.
- Symptoms: small raised bumps.
- Spread: skin contact.
- Treatment: sometimes resolves on its own.
13. Mycoplasma Genitalium
Mycoplasma genitalium is a bacterial STI linked to urethritis and pelvic infections.
- Symptoms: burning, discharge, pelvic pain.
- Treatment: specific antibiotics.
14. Chancroid
Chancroid is a bacterial STI that causes painful sores.
- Symptoms: genital ulcers and swollen lymph nodes.
- Treatment: antibiotics.
15. Lymphogranuloma Venereum (LGV)
LGV is a rare type of chlamydia infection.
- Symptoms: sores, swollen lymph nodes, rectal symptoms.
- Treatment: antibiotics.
16. Granuloma Inguinale (Donovanosis)
This rare bacterial STI causes progressive genital sores.
- Symptoms: painless beefy-red sores.
- Treatment: antibiotics.
17. Ureaplasma
Ureaplasma bacteria may sometimes contribute to urinary or genital symptoms.
- Symptoms: irritation, discharge, pelvic discomfort.
- Treatment: antibiotics when needed.
18. Pelvic Inflammatory Disease (PID)
PID is a serious infection of female reproductive organs, often caused by untreated STIs.
- Symptoms: pelvic pain, fever, discharge.
- Risk: infertility if untreated.
19. Bacterial Vaginosis (BV)
BV is caused by an imbalance of normal vaginal bacteria.
- Symptoms: odor, discharge, irritation.
- Treatment: antibiotics.
20. Yeast Infection
Yeast infections are fungal infections that are not always sexually transmitted but can occur after sex or antibiotic use.
- Symptoms: itching, thick white discharge, irritation.
- Treatment: antifungal medication.
STD/STI Quiz Challenge (30 Questions)
- What does STI stand for?
Answer: Sexually Transmitted Infection. - Can someone have an STI without symptoms?
Answer: Yes. - Which STI is the most common worldwide?
Answer: HPV. - What protects against many STIs?
Answer: Condoms. - Which STI can be prevented with a vaccine?
Answer: HPV and Hepatitis B. - What bacteria causes chlamydia?
Answer: Chlamydia trachomatis. - What STI can cause genital warts?
Answer: HPV. - Can HIV be treated?
Answer: Yes. - What organ does hepatitis affect?
Answer: The liver. - What STI commonly causes painful blisters?
Answer: Herpes. - Can untreated STIs affect fertility?
Answer: Yes. - What parasite causes trichomoniasis?
Answer: Trichomonas vaginalis. - What STI may cause a painless sore?
Answer: Syphilis. - Can oral sex spread STIs?
Answer: Yes. - What does PID stand for?
Answer: Pelvic Inflammatory Disease. - Can condoms reduce HIV risk?
Answer: Yes. - What STI is known as “crabs”?
Answer: Pubic lice. - Can gonorrhea infect the throat?
Answer: Yes. - What STI attacks the immune system?
Answer: HIV. - Can bacterial STIs usually be cured?
Answer: Many can with antibiotics. - What STI is caused by mites?
Answer: Scabies. - What STI often has no symptoms in women?
Answer: Chlamydia. - What medicine type treats fungal infections?
Answer: Antifungal medication. - Can teens get STIs?
Answer: Yes. - Should sexual partners be tested too?
Answer: Yes. - Can STI testing be part of routine healthcare?
Answer: Yes. - What is PrEP used for?
Answer: HIV prevention. - What STI can increase cancer risk?
Answer: HPV. - Can early treatment help prevent complications?
Answer: Yes. - Is getting tested something to feel ashamed about?
Answer: No.
Trusted STD/STI Resources
CDC STD Resource Center
MedlinePlus – STDs
Mayo Clinic
WebMD Sexual Health
NHS Sexual Health
National Institutes of Health (NIH)
FDA
